Sunday, 21st September The Pancreas Summit 2025

• Reprogramming the Immune Microenvironment in Pancreatic Cancer: New Metabolic Targets and Mechanistic Insights - Zaklina Kovacevic
• Assessing the Response of 3D Human Pancreatic Tumour Explants to Standard Chemotherapies - George Sharbeen
• Actin Cytoskeleton Dynamics in Tumor Cells Mediate Immune-Suppressive Microenvironment and Sensitize Pancreas Tumors to PD-1 Blockade Therapy - Bharti Garg
• Decoding the Tumour Microenvironment of Pancreatic Cancer Through Multi-Omics Approaches - Daniela Loessner
• GOT1 Inhibition Reshapes the Extracellular Matrix of Pancreatic Cancer - Rodrigo Curvello
• Targeting Circulating Hsp70 and Hsp90 to Mitigate Muscle Wasting in a Patient-Derived Xenograft Pancreatic Cancer Model in Mice - Yi-Ping Li

• Imaging, Antibiotics, Nutrition - Vinciane Rebours
• Prognosis, Analgesia, and Fluid Therapy  - Santhi Swaroop Vege
• Treatment of Infected Necrotizing Pancreatitis - Timothy Gardner
• Endoscopic Rx for Biliary AP, Prevention of Post-ERCP AP - Nageshwar Reddy Duvvur
• Summary of the Updates: 2025 Guidelines - Pramod Garg

• A Multinational Study on Chronic Pancreatitis in Southeast and South Asia (CPSEASA) - Misbah Unnisa
• The Changing and Persistent Landscape of Pancreatic Cystic Lesions: A Three-Decade Prospective Single-Center Experience with Over 5,000 Consecutive Cases - Hiroki Oyama

• Extracellular Vesicle Proteome of Pancreatic Cancer Highlights Sodium/Myo-Inositol Cotransporter as a Potential Oncogenic Biomarker - Marco Falasca
• Spatial Transcriptomics Assessing Native Cell Populations and Their Representation in Pancreatic Cancer (Sub)Types - Ilse Rooman
• Develop a Novel Therapy for Pancreatic Cancer - Min Li
• Protein Biomarkers for Pancreatic Cancer Detection: Progress, Challenges, and Future Directions - Eithne Costello
• Panel Discussion - Panel Members

Chairs: Stephen Philcox, Andrew Metz, Albrecht Neesse

• Panel Discussion - Savannah Morrison, Linda Zhang, Motaz Ashkar, Kyoichi Takaori, Shounak Majumder and David Holcdorf
• APRISE Study - Andrew Metz

• Latest Updates in the Microbiome Field: Where Are We Now? - Emad El-Omar
• The Gut-Pancreas Axis – Implications for Pancreatic Diseases - Albrecht Neesse
• A Physiologically Relevant 3D PDAC Organoid Model Capturing CAF Heterogeneity for Tumour Microenvironment-Driven Therapeutic Discovery - Yujie Li
• PICALM in Pancreatic Stellate Cell and Cancer Cell Coculture-Derived Exosomes – Mediator of Pancreatic Cancer-Related Diabetes? - Helen Binang
• Immune Profiling of Pancreatic Ductal Adenocarcinoma Using Multiplex Immunohistochemistry Reveals Prognostic and Predictive Biomarkers - Ryan Munnings
• Insulin-Induced Secretion of Exosomal TNFAIP8 from Tumor Cells Promotes Pancreatic Cancer Fibrosis via STAT1 Ubiquitination in Cancer-Associated Fibroblasts - Zhenyu Li

• Algorithm for Diagnosing the Cause of RAP - Shounak Majumder
• Pancreatitis Related to IgG4 Disease: Strategies of Treatment - Vinciane Rebours
• Progression of Fibroinflammatory Disorders of the Pancreas Mechanisms and Opportunities - Stephen Pandol
• Nutrition on PEI - Kate Furness